mirror of
https://github.com/pcvolkmer/etl-processor.git
synced 2025-07-17 12:52:54 +00:00
3237 lines
98 KiB
JSON
3237 lines
98 KiB
JSON
{
|
|
"patient": {
|
|
"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
|
|
"gender": {
|
|
"code": "female",
|
|
"display": "Weiblich",
|
|
"system": "Gender"
|
|
},
|
|
"birthDate": "1994-05-25",
|
|
"dateOfDeath": "2018-05-25",
|
|
"healthInsurance": {
|
|
"type": {
|
|
"code": "GKV",
|
|
"display": "gesetzliche Krankenversicherung",
|
|
"system": "http://fhir.de/CodeSystem/versicherungsart-de-basis"
|
|
},
|
|
"reference": {
|
|
"id": "1234567890",
|
|
"system": "https://www.dguv.de/arge-ik",
|
|
"display": "AOK",
|
|
"type": "HealthInsurance"
|
|
}
|
|
},
|
|
"address": {
|
|
"municipalityCode": "12345"
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|
},
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|
"age": {
|
|
"value": 24,
|
|
"unit": "Years"
|
|
},
|
|
"vitalStatus": {
|
|
"code": "deceased",
|
|
"display": "Verstorben",
|
|
"system": "dnpm-dip/patient/vital-status"
|
|
}
|
|
},
|
|
"episodesOfCare": [
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{
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|
"id": "fc02c478-86f6-4910-9ea1-8a0d1e435c83",
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"patient": {
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"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
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"type": "Patient"
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|
},
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"period": {
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"start": "2025-01-04"
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},
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|
"diagnoses": [
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|
{
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|
"id": "efa999e3-6006-4a76-90f9-32786b5f0531",
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"type": "MTBDiagnosis"
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}
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|
]
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}
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|
],
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"diagnoses": [
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|
{
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"id": "efa999e3-6006-4a76-90f9-32786b5f0531",
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"patient": {
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"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
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"type": "Patient"
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},
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"recordedOn": "2016-01-25",
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"type": {
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|
"history": [
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{
|
|
"value": {
|
|
"code": "main",
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|
"display": "Hauptdiagnose",
|
|
"system": "dnpm-dip/mtb/diagnosis/type"
|
|
},
|
|
"date": "2016-01-25"
|
|
}
|
|
]
|
|
},
|
|
"code": {
|
|
"code": "C50.2",
|
|
"display": "Bösartige Neubildung: Oberer innerer Quadrant der Brustdrüse",
|
|
"system": "http://fhir.de/CodeSystem/bfarm/icd-10-gm",
|
|
"version": "2025"
|
|
},
|
|
"topography": {
|
|
"code": "C50.2",
|
|
"display": "Oberer innerer Quadrant der Brust",
|
|
"system": "urn:oid:2.16.840.1.113883.6.43.1",
|
|
"version": "Zweite Revision"
|
|
},
|
|
"grading": {
|
|
"history": [
|
|
{
|
|
"date": "2016-01-25",
|
|
"codes": [
|
|
{
|
|
"code": "1",
|
|
"display": "1 = gut differenziert",
|
|
"system": "https://www.basisdatensatz.de/feld/161/grading"
|
|
},
|
|
{
|
|
"code": "4",
|
|
"display": "Glioblastoma",
|
|
"system": "dnpm-dip/mtb/who-grading-cns-tumors",
|
|
"version": "2021"
|
|
}
|
|
]
|
|
}
|
|
]
|
|
},
|
|
"staging": {
|
|
"history": [
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|
{
|
|
"date": "2016-01-25",
|
|
"method": {
|
|
"code": "clinical",
|
|
"display": "Klinisch",
|
|
"system": "dnpm-dip/mtb/tumor-staging/method"
|
|
},
|
|
"tnmClassification": {
|
|
"tumor": {
|
|
"code": "T2",
|
|
"system": "UICC"
|
|
},
|
|
"nodes": {
|
|
"code": "N1",
|
|
"system": "UICC"
|
|
},
|
|
"metastasis": {
|
|
"code": "Mx",
|
|
"system": "UICC"
|
|
}
|
|
},
|
|
"otherClassifications": [
|
|
{
|
|
"code": "local",
|
|
"display": "Lokal",
|
|
"system": "dnpm-dip/mtb/diagnosis/kds-tumor-spread"
|
|
}
|
|
]
|
|
}
|
|
]
|
|
},
|
|
"guidelineTreatmentStatus": {
|
|
"code": "no-guidelines-available",
|
|
"display": "Keine Leitlinien vorhanden",
|
|
"system": "dnpm-dip/mtb/diagnosis/guideline-treatment-status"
|
|
},
|
|
"notes": [
|
|
"Notes on the tumor diagnosis..."
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|
]
|
|
}
|
|
],
|
|
"familyMemberHistories": [
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{
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|
"id": "ba866f34-5681-4446-b635-6ff90e4d03ab",
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"patient": {
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"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
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|
"type": "Patient"
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|
},
|
|
"relationship": {
|
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"code": "FAMMEMB",
|
|
"display": "Verwandter ersten Grades",
|
|
"system": "dnpm-dip/mtb/family-meber-history/relationship-type"
|
|
}
|
|
}
|
|
],
|
|
"guidelineTherapies": [
|
|
{
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"id": "9a89aea6-3305-49f3-94e2-dfe347989dec",
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"patient": {
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"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
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"type": "Patient"
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|
},
|
|
"reason": {
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|
"id": "efa999e3-6006-4a76-90f9-32786b5f0531",
|
|
"display": "Bösartige Neubildung: Oberer innerer Quadrant der Brustdrüse",
|
|
"type": "MTBDiagnosis"
|
|
},
|
|
"therapyLine": 3,
|
|
"intent": {
|
|
"code": "X",
|
|
"display": "Keine Angabe",
|
|
"system": "dnpm-dip/therapy/intent"
|
|
},
|
|
"category": {
|
|
"code": "O",
|
|
"display": "Ohne Bezug zur operativen Therapie",
|
|
"system": "dnpm-dip/therapy/category"
|
|
},
|
|
"recordedOn": "2025-07-04",
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|
"status": {
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|
"code": "stopped",
|
|
"display": "Abgebrochen",
|
|
"system": "dnpm-dip/therapy/status"
|
|
},
|
|
"statusReason": {
|
|
"code": "progression",
|
|
"display": "Progression",
|
|
"system": "dnpm-dip/therapy/status-reason"
|
|
},
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|
"period": {
|
|
"start": "2024-07-04",
|
|
"end": "2024-09-12"
|
|
},
|
|
"medication": [
|
|
{
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"code": "L01FX26",
|
|
"display": "Mirvetuximab soravtansin",
|
|
"system": "http://fhir.de/CodeSystem/bfarm/atc",
|
|
"version": "2025"
|
|
}
|
|
],
|
|
"notes": [
|
|
"Notes on the therapy..."
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|
]
|
|
}
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|
],
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|
"guidelineProcedures": [
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{
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"id": "99831a57-e26e-45f4-a9d2-cf41f6ef6560",
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"patient": {
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"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
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"type": "Patient"
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},
|
|
"reason": {
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|
"id": "efa999e3-6006-4a76-90f9-32786b5f0531",
|
|
"display": "Bösartige Neubildung: Oberer innerer Quadrant der Brustdrüse",
|
|
"type": "MTBDiagnosis"
|
|
},
|
|
"therapyLine": 7,
|
|
"intent": {
|
|
"code": "K",
|
|
"display": "Kurativ",
|
|
"system": "dnpm-dip/therapy/intent"
|
|
},
|
|
"code": {
|
|
"code": "radio-therapy",
|
|
"display": "Strahlen-Therapie",
|
|
"system": "dnpm-dip/mtb/procedure/type"
|
|
},
|
|
"status": {
|
|
"code": "stopped",
|
|
"display": "Abgebrochen",
|
|
"system": "dnpm-dip/therapy/status"
|
|
},
|
|
"statusReason": {
|
|
"code": "patient-death",
|
|
"display": "Tod",
|
|
"system": "dnpm-dip/therapy/status-reason"
|
|
},
|
|
"recordedOn": "2025-07-04",
|
|
"period": {
|
|
"start": "2025-01-04"
|
|
},
|
|
"notes": [
|
|
"Notes on the therapeutic procedure..."
|
|
]
|
|
}
|
|
],
|
|
"performanceStatus": [
|
|
{
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|
"id": "6cc2bd40-4193-4814-aa30-54c6dd1dea7d",
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|
"patient": {
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"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
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|
"type": "Patient"
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|
},
|
|
"effectiveDate": "2025-07-04",
|
|
"value": {
|
|
"code": "4",
|
|
"display": "ECOG 4",
|
|
"system": "ECOG-Performance-Status"
|
|
}
|
|
}
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|
],
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|
"specimens": [
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{
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|
"id": "6abae7ae-1308-4637-8093-0be6594a5bc4",
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"patient": {
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"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
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"type": "Patient"
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},
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"diagnosis": {
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|
"id": "efa999e3-6006-4a76-90f9-32786b5f0531",
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|
"type": "MTBDiagnosis"
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|
},
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|
"type": {
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|
"code": "unknown",
|
|
"display": "Unbekannt",
|
|
"system": "dnpm-dip/mtb/tumor-specimen/type"
|
|
},
|
|
"collection": {
|
|
"date": "2025-07-04",
|
|
"method": {
|
|
"code": "cytology",
|
|
"display": "Zytologie",
|
|
"system": "dnpm-dip/mtb/tumor-specimen/collection/method"
|
|
},
|
|
"localization": {
|
|
"code": "regional-lymph-nodes",
|
|
"display": "Regionäre Lymphknoten",
|
|
"system": "dnpm-dip/mtb/tumor-specimen/collection/localization"
|
|
}
|
|
}
|
|
}
|
|
],
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|
"priorDiagnosticReports": [
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{
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"id": "e23f3cc9-19ea-477e-a72e-696618064e91",
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|
"patient": {
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"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
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|
"type": "Patient"
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|
},
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|
"performer": {
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|
"id": "xyz",
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|
"display": "Molekular-Pathologie UKx",
|
|
"type": "Institute"
|
|
},
|
|
"issuedOn": "2025-07-04",
|
|
"specimen": {
|
|
"id": "6abae7ae-1308-4637-8093-0be6594a5bc4",
|
|
"type": "TumorSpecimen"
|
|
},
|
|
"type": {
|
|
"code": "fusion-panel",
|
|
"display": "Fusionspanel",
|
|
"system": "dnpm-dip/mtb/molecular-diagnostics/type"
|
|
},
|
|
"results": [
|
|
"Result of diagnostics..."
|
|
]
|
|
}
|
|
],
|
|
"histologyReports": [
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|
{
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|
"id": "138c56dc-b90a-4737-b89d-0422e9323cac",
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"patient": {
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"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
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"type": "Patient"
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|
},
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|
"specimen": {
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|
"id": "6abae7ae-1308-4637-8093-0be6594a5bc4",
|
|
"type": "TumorSpecimen"
|
|
},
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|
"issuedOn": "2025-07-04",
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|
"results": {
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|
"tumorMorphology": {
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"id": "79d857bc-0726-4f59-8add-995943f93670",
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"patient": {
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"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
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"type": "Patient"
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|
},
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|
"specimen": {
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|
"id": "6abae7ae-1308-4637-8093-0be6594a5bc4",
|
|
"type": "TumorSpecimen"
|
|
},
|
|
"value": {
|
|
"code": "9372/3",
|
|
"display": "Entdifferenziertes Chordom",
|
|
"system": "urn:oid:2.16.840.1.113883.6.43.1",
|
|
"version": "Zweite Revision"
|
|
},
|
|
"note": "Notes..."
|
|
},
|
|
"tumorCellContent": {
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|
"id": "0fa34021-6083-49da-b176-2be816b77e4f",
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|
"patient": {
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"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
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|
"type": "Patient"
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|
},
|
|
"specimen": {
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|
"id": "6abae7ae-1308-4637-8093-0be6594a5bc4",
|
|
"type": "TumorSpecimen"
|
|
},
|
|
"method": {
|
|
"code": "histologic",
|
|
"display": "Histologisch",
|
|
"system": "dnpm-dip/mtb/tumor-cell-content/method"
|
|
},
|
|
"value": 0.639758904015403
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|
}
|
|
}
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|
}
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|
],
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|
"ihcReports": [
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{
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|
"id": "678bc235-4a27-4fcd-88ab-8d682184e5c0",
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|
"patient": {
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|
"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
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|
"type": "Patient"
|
|
},
|
|
"specimen": {
|
|
"id": "6abae7ae-1308-4637-8093-0be6594a5bc4",
|
|
"type": "TumorSpecimen"
|
|
},
|
|
"issuedOn": "2025-07-04",
|
|
"results": {
|
|
"proteinExpression": [
|
|
{
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|
"id": "30e22700-b895-4ee6-8f1e-fee9a82d15a7",
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|
"patient": {
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|
"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
|
|
"type": "Patient"
|
|
},
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|
"protein": {
|
|
"code": "HGNC:886",
|
|
"display": "ATRX",
|
|
"system": "https://www.genenames.org/"
|
|
},
|
|
"value": {
|
|
"code": "exp",
|
|
"display": "Exprimiert",
|
|
"system": "dnpm-dip/mtb/ihc/protein-expression/result"
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|
},
|
|
"tpsScore": 58,
|
|
"icScore": {
|
|
"code": "3",
|
|
"display": ">= 10%",
|
|
"system": "dnpm-dip/mtb/ihc/protein-expression/ic-score"
|
|
},
|
|
"tcScore": {
|
|
"code": "4",
|
|
"display": ">= 25%",
|
|
"system": "dnpm-dip/mtb/ihc/protein-expression/tc-score"
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|
}
|
|
},
|
|
{
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|
"id": "f465d53e-bfab-4392-bcb9-15ff83c92b11",
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"patient": {
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"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
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|
"type": "Patient"
|
|
},
|
|
"protein": {
|
|
"code": "HGNC:5173",
|
|
"display": "HRAS",
|
|
"system": "https://www.genenames.org/"
|
|
},
|
|
"value": {
|
|
"code": "exp",
|
|
"display": "Exprimiert",
|
|
"system": "dnpm-dip/mtb/ihc/protein-expression/result"
|
|
},
|
|
"tpsScore": 25,
|
|
"icScore": {
|
|
"code": "1",
|
|
"display": ">= 1%",
|
|
"system": "dnpm-dip/mtb/ihc/protein-expression/ic-score"
|
|
},
|
|
"tcScore": {
|
|
"code": "4",
|
|
"display": ">= 25%",
|
|
"system": "dnpm-dip/mtb/ihc/protein-expression/tc-score"
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|
}
|
|
},
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|
{
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|
"id": "0d2acf7d-2a6d-49d3-842b-574684e94f03",
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|
"patient": {
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|
"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
|
|
"type": "Patient"
|
|
},
|
|
"protein": {
|
|
"code": "HGNC:6407",
|
|
"display": "KRAS",
|
|
"system": "https://www.genenames.org/"
|
|
},
|
|
"value": {
|
|
"code": "unknown",
|
|
"display": "untersucht, kein Ergebnis",
|
|
"system": "dnpm-dip/mtb/ihc/protein-expression/result"
|
|
},
|
|
"tpsScore": 31,
|
|
"icScore": {
|
|
"code": "1",
|
|
"display": ">= 1%",
|
|
"system": "dnpm-dip/mtb/ihc/protein-expression/ic-score"
|
|
},
|
|
"tcScore": {
|
|
"code": "1",
|
|
"display": ">= 1%",
|
|
"system": "dnpm-dip/mtb/ihc/protein-expression/tc-score"
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|
}
|
|
},
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|
{
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|
"id": "71c3c5f9-8859-466c-a086-e05f4d454429",
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"patient": {
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"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
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|
"type": "Patient"
|
|
},
|
|
"protein": {
|
|
"code": "HGNC:3689",
|
|
"display": "FGFR2",
|
|
"system": "https://www.genenames.org/"
|
|
},
|
|
"value": {
|
|
"code": "not-exp",
|
|
"display": "Nicht exprimiert",
|
|
"system": "dnpm-dip/mtb/ihc/protein-expression/result"
|
|
},
|
|
"tpsScore": 65,
|
|
"icScore": {
|
|
"code": "1",
|
|
"display": ">= 1%",
|
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"code": "progression",
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|
"display": "Progression",
|
|
"system": "dnpm-dip/therapy/status-reason"
|
|
},
|
|
"recommendationFulfillmentStatus": {
|
|
"code": "complete",
|
|
"display": "Komplett",
|
|
"system": "dnpm-dip/therapy/recommendation-fulfillment-status"
|
|
},
|
|
"dosage": {
|
|
"code": "under-50%",
|
|
"display": "< 50 %",
|
|
"system": "dnpm-dip/therapy/dosage-density"
|
|
},
|
|
"period": {
|
|
"start": "2018-02-23",
|
|
"end": "2018-05-25"
|
|
},
|
|
"medication": [
|
|
{
|
|
"code": "L01EN02",
|
|
"display": "Pemigatinib",
|
|
"system": "http://fhir.de/CodeSystem/bfarm/atc",
|
|
"version": "2025"
|
|
}
|
|
],
|
|
"notes": [
|
|
"Notes on the therapy..."
|
|
]
|
|
}
|
|
]
|
|
},
|
|
{
|
|
"history": [
|
|
{
|
|
"id": "98847b9b-2e7c-44d2-aa6c-cf9f48e0136e",
|
|
"patient": {
|
|
"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
|
|
"type": "Patient"
|
|
},
|
|
"reason": {
|
|
"id": "efa999e3-6006-4a76-90f9-32786b5f0531",
|
|
"display": "Bösartige Neubildung: Oberer innerer Quadrant der Brustdrüse",
|
|
"type": "MTBDiagnosis"
|
|
},
|
|
"intent": {
|
|
"code": "X",
|
|
"display": "Keine Angabe",
|
|
"system": "dnpm-dip/therapy/intent"
|
|
},
|
|
"category": {
|
|
"code": "O",
|
|
"display": "Ohne Bezug zur operativen Therapie",
|
|
"system": "dnpm-dip/therapy/category"
|
|
},
|
|
"basedOn": {
|
|
"id": "49ba8a62-0798-4c4c-88cc-0afba7c2a56e",
|
|
"type": "MTBMedicationRecommendation"
|
|
},
|
|
"recordedOn": "2025-07-04",
|
|
"status": {
|
|
"code": "stopped",
|
|
"display": "Abgebrochen",
|
|
"system": "dnpm-dip/therapy/status"
|
|
},
|
|
"statusReason": {
|
|
"code": "progression",
|
|
"display": "Progression",
|
|
"system": "dnpm-dip/therapy/status-reason"
|
|
},
|
|
"recommendationFulfillmentStatus": {
|
|
"code": "complete",
|
|
"display": "Komplett",
|
|
"system": "dnpm-dip/therapy/recommendation-fulfillment-status"
|
|
},
|
|
"dosage": {
|
|
"code": "under-50%",
|
|
"display": "< 50 %",
|
|
"system": "dnpm-dip/therapy/dosage-density"
|
|
},
|
|
"period": {
|
|
"start": "2017-10-27",
|
|
"end": "2018-05-25"
|
|
},
|
|
"medication": [
|
|
{
|
|
"code": "L01XA01",
|
|
"display": "Cisplatin",
|
|
"system": "http://fhir.de/CodeSystem/bfarm/atc",
|
|
"version": "2025"
|
|
}
|
|
],
|
|
"notes": [
|
|
"Notes on the therapy..."
|
|
]
|
|
}
|
|
]
|
|
}
|
|
],
|
|
"responses": [
|
|
{
|
|
"id": "98d80143-3ad2-4cfe-bf29-d04e73d78728",
|
|
"patient": {
|
|
"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
|
|
"type": "Patient"
|
|
},
|
|
"therapy": {
|
|
"id": "6ac97a41-99a1-4a08-9db4-41a8698c7401",
|
|
"type": "MTBSystemicTherapy"
|
|
},
|
|
"effectiveDate": "2018-04-20",
|
|
"method": {
|
|
"code": "RECIST",
|
|
"display": "Nach RECIST-Kriterien",
|
|
"system": "dnpm-dip/mtb/response/method"
|
|
},
|
|
"value": {
|
|
"code": "MR",
|
|
"display": "Mixed Response",
|
|
"system": "RECIST"
|
|
}
|
|
},
|
|
{
|
|
"id": "f804a75c-d378-4eec-84c3-274fa20416bc",
|
|
"patient": {
|
|
"id": "644bae7a-56f6-4ee8-b02f-c532e65af5b1",
|
|
"type": "Patient"
|
|
},
|
|
"therapy": {
|
|
"id": "98847b9b-2e7c-44d2-aa6c-cf9f48e0136e",
|
|
"type": "MTBSystemicTherapy"
|
|
},
|
|
"effectiveDate": "2018-01-19",
|
|
"method": {
|
|
"code": "RANO",
|
|
"display": "Nach RANO-Kriterien",
|
|
"system": "dnpm-dip/mtb/response/method"
|
|
},
|
|
"value": {
|
|
"code": "PD",
|
|
"display": "Progressive Disease",
|
|
"system": "RECIST"
|
|
}
|
|
}
|
|
]
|
|
} |