mirror of
https://github.com/dnpm-dip/mv64e-mtb-dto-go.git
synced 2025-07-01 18:32:55 +00:00
2244 lines
66 KiB
JSON
2244 lines
66 KiB
JSON
{
|
|
"patient" : {
|
|
"id" : "63f8fd7b-8127-4f3c-8843-aa9199e21c29",
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|
"gender" : {
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|
"code" : "female",
|
|
"display" : "Weiblich",
|
|
"system" : "Gender"
|
|
},
|
|
"birthDate" : "1956-02-25",
|
|
"dateOfDeath" : "2007-02-25",
|
|
"healthInsurance" : {
|
|
"type" : {
|
|
"code" : "GKV",
|
|
"display" : "gesetzliche Krankenversicherung",
|
|
"system" : "http://fhir.de/CodeSystem/versicherungsart-de-basis"
|
|
},
|
|
"reference" : {
|
|
"id" : "1234567890",
|
|
"system" : "https://www.dguv.de/arge-ik",
|
|
"display" : "AOK",
|
|
"type" : "HealthInsurance"
|
|
}
|
|
},
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|
"address" : {
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|
"municipalityCode" : "12345"
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},
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"age" : {
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"value" : 51,
|
|
"unit" : "Years"
|
|
},
|
|
"vitalStatus" : {
|
|
"code" : "deceased",
|
|
"display" : "Verstorben",
|
|
"system" : "dnpm-dip/patient/vital-status"
|
|
}
|
|
},
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|
"episodesOfCare" : [ {
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"id" : "a95f44a6-5dbb-4acd-9d52-05db10f8410b",
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"patient" : {
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"id" : "63f8fd7b-8127-4f3c-8843-aa9199e21c29",
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"type" : "Patient"
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},
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"period" : {
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"start" : "2024-10-03"
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},
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"diagnoses" : [ {
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|
"id" : "744bf622-ba4b-4e64-867c-0807847d9da4",
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"type" : "MTBDiagnosis"
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} ]
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} ],
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"diagnoses" : [ {
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"id" : "744bf622-ba4b-4e64-867c-0807847d9da4",
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"patient" : {
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"id" : "63f8fd7b-8127-4f3c-8843-aa9199e21c29",
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"type" : "Patient"
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},
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"recordedOn" : "2004-01-25",
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"type" : {
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|
"history" : [ {
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"value" : {
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|
"code" : "main",
|
|
"display" : "Hauptdiagnose",
|
|
"system" : "dnpm-dip/mtb/diagnosis/type"
|
|
},
|
|
"date" : "2004-01-25"
|
|
} ]
|
|
},
|
|
"code" : {
|
|
"code" : "C69.0",
|
|
"display" : "Bösartige Neubildung: Konjunktiva",
|
|
"system" : "http://fhir.de/CodeSystem/bfarm/icd-10-gm",
|
|
"version" : "2025"
|
|
},
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|
"topography" : {
|
|
"code" : "C69.0",
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|
"display" : "Konjunktiva",
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|
"system" : "urn:oid:2.16.840.1.113883.6.43.1",
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|
"version" : "Zweite Revision"
|
|
},
|
|
"grading" : {
|
|
"history" : [ {
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|
"date" : "2004-01-25",
|
|
"codes" : [ {
|
|
"code" : "U",
|
|
"display" : "U = unbekannt",
|
|
"system" : "https://www.basisdatensatz.de/feld/161/grading"
|
|
}, {
|
|
"code" : "4",
|
|
"display" : "Glioblastoma",
|
|
"system" : "dnpm-dip/mtb/who-grading-cns-tumors",
|
|
"version" : "2021"
|
|
} ]
|
|
} ]
|
|
},
|
|
"staging" : {
|
|
"history" : [ {
|
|
"date" : "2004-01-25",
|
|
"method" : {
|
|
"code" : "clinical",
|
|
"display" : "Klinisch",
|
|
"system" : "dnpm-dip/mtb/tumor-staging/method"
|
|
},
|
|
"tnmClassification" : {
|
|
"tumor" : {
|
|
"code" : "T1",
|
|
"system" : "UICC"
|
|
},
|
|
"nodes" : {
|
|
"code" : "N2",
|
|
"system" : "UICC"
|
|
},
|
|
"metastasis" : {
|
|
"code" : "Mx",
|
|
"system" : "UICC"
|
|
}
|
|
},
|
|
"otherClassifications" : [ {
|
|
"code" : "metastasized",
|
|
"display" : "Metastasiert",
|
|
"system" : "dnpm-dip/mtb/diagnosis/kds-tumor-spread"
|
|
} ]
|
|
} ]
|
|
},
|
|
"guidelineTreatmentStatus" : {
|
|
"code" : "non-exhausted",
|
|
"display" : "Leitlinien nicht ausgeschöpft",
|
|
"system" : "dnpm-dip/mtb/diagnosis/guideline-treatment-status"
|
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},
|
|
"notes" : [ "Notes on the tumor diagnosis..." ]
|
|
} ],
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"guidelineTherapies" : [ {
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"id" : "a3a6a53f-d531-4f46-8697-9052d98cc9e5",
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"patient" : {
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"id" : "63f8fd7b-8127-4f3c-8843-aa9199e21c29",
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"type" : "Patient"
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},
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"reason" : {
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|
"id" : "744bf622-ba4b-4e64-867c-0807847d9da4",
|
|
"display" : "Bösartige Neubildung: Konjunktiva",
|
|
"type" : "MTBDiagnosis"
|
|
},
|
|
"therapyLine" : 2,
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|
"intent" : {
|
|
"code" : "S",
|
|
"display" : "Sonstiges",
|
|
"system" : "dnpm-dip/therapy/intent"
|
|
},
|
|
"category" : {
|
|
"code" : "I",
|
|
"display" : "Intraopterativ",
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|
"system" : "dnpm-dip/therapy/category"
|
|
},
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|
"recordedOn" : "2025-04-03",
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|
"status" : {
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"code" : "stopped",
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|
"display" : "Abgebrochen",
|
|
"system" : "dnpm-dip/therapy/status"
|
|
},
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|
"statusReason" : {
|
|
"code" : "progression",
|
|
"display" : "Progression",
|
|
"system" : "dnpm-dip/therapy/status-reason"
|
|
},
|
|
"period" : {
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|
"start" : "2023-08-03",
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|
"end" : "2024-01-18"
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|
},
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|
"medication" : [ {
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|
"code" : "L01EX24",
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|
"display" : "Surufatinib",
|
|
"system" : "http://fhir.de/CodeSystem/bfarm/atc",
|
|
"version" : "2024"
|
|
} ],
|
|
"notes" : [ "Notes on the therapy..." ]
|
|
} ],
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|
"guidelineProcedures" : [ {
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"id" : "ff5148ce-94ab-487f-a2a4-ebc5e1ea8a53",
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"patient" : {
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"id" : "63f8fd7b-8127-4f3c-8843-aa9199e21c29",
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"type" : "Patient"
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},
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"reason" : {
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|
"id" : "744bf622-ba4b-4e64-867c-0807847d9da4",
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|
"display" : "Bösartige Neubildung: Konjunktiva",
|
|
"type" : "MTBDiagnosis"
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|
},
|
|
"therapyLine" : 1,
|
|
"intent" : {
|
|
"code" : "K",
|
|
"display" : "Kurativ",
|
|
"system" : "dnpm-dip/therapy/intent"
|
|
},
|
|
"code" : {
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|
"code" : "surgery",
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|
"display" : "OP",
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|
"system" : "dnpm-dip/mtb/procedure/type"
|
|
},
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|
"status" : {
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|
"code" : "completed",
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|
"display" : "Abgeschlossen",
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|
"system" : "dnpm-dip/therapy/status"
|
|
},
|
|
"statusReason" : {
|
|
"code" : "chronic-remission",
|
|
"display" : "Anhaltende Remission",
|
|
"system" : "dnpm-dip/therapy/status-reason"
|
|
},
|
|
"recordedOn" : "2025-04-03",
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|
"period" : {
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|
"start" : "2024-10-03"
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|
},
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|
"notes" : [ "Notes on the therapeutic procedure..." ]
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|
}, {
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|
"id" : "461105eb-c3c6-4fd4-bcd3-799e7eaf281d",
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"patient" : {
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"id" : "63f8fd7b-8127-4f3c-8843-aa9199e21c29",
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"type" : "Patient"
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},
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"reason" : {
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|
"id" : "744bf622-ba4b-4e64-867c-0807847d9da4",
|
|
"display" : "Bösartige Neubildung: Konjunktiva",
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|
"type" : "MTBDiagnosis"
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|
},
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|
"therapyLine" : 8,
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|
"intent" : {
|
|
"code" : "K",
|
|
"display" : "Kurativ",
|
|
"system" : "dnpm-dip/therapy/intent"
|
|
},
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|
"code" : {
|
|
"code" : "nuclear-medicine",
|
|
"display" : "Nuklearmedizinische Therapie",
|
|
"system" : "dnpm-dip/mtb/procedure/type"
|
|
},
|
|
"status" : {
|
|
"code" : "stopped",
|
|
"display" : "Abgebrochen",
|
|
"system" : "dnpm-dip/therapy/status"
|
|
},
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|
"statusReason" : {
|
|
"code" : "progression",
|
|
"display" : "Progression",
|
|
"system" : "dnpm-dip/therapy/status-reason"
|
|
},
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|
"recordedOn" : "2025-04-03",
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|
"period" : {
|
|
"start" : "2024-10-03"
|
|
},
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|
"notes" : [ "Notes on the therapeutic procedure..." ]
|
|
} ],
|
|
"performanceStatus" : [ {
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|
"id" : "2b1522a8-9628-4e66-8769-e1f329bf37c5",
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|
"patient" : {
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"id" : "63f8fd7b-8127-4f3c-8843-aa9199e21c29",
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|
"type" : "Patient"
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|
},
|
|
"effectiveDate" : "2025-04-03",
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|
"value" : {
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|
"code" : "3",
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|
"display" : "ECOG 3",
|
|
"system" : "ECOG-Performance-Status"
|
|
}
|
|
} ],
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|
"specimens" : [ {
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|
"id" : "b0557dde-6e54-4d01-8982-7ff88313adaa",
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|
"patient" : {
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|
"id" : "63f8fd7b-8127-4f3c-8843-aa9199e21c29",
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|
"type" : "Patient"
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|
},
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|
"diagnosis" : {
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|
"id" : "744bf622-ba4b-4e64-867c-0807847d9da4",
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|
"type" : "MTBDiagnosis"
|
|
},
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|
"type" : {
|
|
"code" : "FFPE",
|
|
"display" : "FFPE",
|
|
"system" : "dnpm-dip/mtb/tumor-specimen/type"
|
|
},
|
|
"collection" : {
|
|
"date" : "2025-04-03",
|
|
"method" : {
|
|
"code" : "unknown",
|
|
"display" : "Unbekannt",
|
|
"system" : "dnpm-dip/mtb/tumor-specimen/collection/method"
|
|
},
|
|
"localization" : {
|
|
"code" : "unknown",
|
|
"display" : "Unbekannt",
|
|
"system" : "dnpm-dip/mtb/tumor-specimen/collection/localization"
|
|
}
|
|
}
|
|
} ],
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|
"priorDiagnosticReports" : [ {
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"id" : "e3d6eb01-6afb-4cb2-8682-b5f67565a701",
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"patient" : {
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|
"id" : "63f8fd7b-8127-4f3c-8843-aa9199e21c29",
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|
"type" : "Patient"
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|
},
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|
"performer" : {
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|
"id" : "xyz",
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|
"display" : "Molekular-Pathologie UKx",
|
|
"type" : "Institute"
|
|
},
|
|
"issuedOn" : "2025-04-03",
|
|
"specimen" : {
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|
"id" : "b0557dde-6e54-4d01-8982-7ff88313adaa",
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|
"type" : "TumorSpecimen"
|
|
},
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|
"type" : {
|
|
"code" : "other",
|
|
"display" : "Other",
|
|
"system" : "dnpm-dip/mtb/molecular-diagnostics/type"
|
|
},
|
|
"results" : [ "Result of diagnostics..." ]
|
|
} ],
|
|
"histologyReports" : [ {
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|
"id" : "49154f97-84a9-4a8c-8f52-b5dcbf6973ce",
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"patient" : {
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"id" : "63f8fd7b-8127-4f3c-8843-aa9199e21c29",
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|
"type" : "Patient"
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|
},
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|
"specimen" : {
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|
"id" : "b0557dde-6e54-4d01-8982-7ff88313adaa",
|
|
"type" : "TumorSpecimen"
|
|
},
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|
"issuedOn" : "2025-04-03",
|
|
"results" : {
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|
"tumorMorphology" : {
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|
"id" : "af23d218-7c03-4950-984c-a5c35295b696",
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|
"patient" : {
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"id" : "63f8fd7b-8127-4f3c-8843-aa9199e21c29",
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"type" : "Patient"
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|
},
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|
"specimen" : {
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|
"id" : "b0557dde-6e54-4d01-8982-7ff88313adaa",
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|
"type" : "TumorSpecimen"
|
|
},
|
|
"value" : {
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|
"code" : "8935/1",
|
|
"display" : "Stromatumor o.n.A.",
|
|
"system" : "urn:oid:2.16.840.1.113883.6.43.1",
|
|
"version" : "Zweite Revision"
|
|
},
|
|
"notes" : "Notes..."
|
|
},
|
|
"tumorCellContent" : {
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|
"id" : "f45c7add-f441-4786-aff3-917bad76b140",
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|
"patient" : {
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"id" : "63f8fd7b-8127-4f3c-8843-aa9199e21c29",
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|
"type" : "Patient"
|
|
},
|
|
"specimen" : {
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|
"id" : "b0557dde-6e54-4d01-8982-7ff88313adaa",
|
|
"type" : "TumorSpecimen"
|
|
},
|
|
"method" : {
|
|
"code" : "histologic",
|
|
"display" : "Histologisch",
|
|
"system" : "dnpm-dip/mtb/tumor-cell-content/method"
|
|
},
|
|
"value" : 0.8229387003304868
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|
}
|
|
}
|
|
} ],
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|
"ihcReports" : [ {
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|
"id" : "dfc2429b-4677-4c04-8359-2e8bd68e8006",
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|
"patient" : {
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"id" : "63f8fd7b-8127-4f3c-8843-aa9199e21c29",
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|
"type" : "Patient"
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|
},
|
|
"specimen" : {
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|
"id" : "b0557dde-6e54-4d01-8982-7ff88313adaa",
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|
"type" : "TumorSpecimen"
|
|
},
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|
"issuedOn" : "2025-04-03",
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|
"journalId" : "9dc66c04-ad2c-4d4c-9e38-b524e4e59c4a",
|
|
"blockIds" : [ "34c921a8-d047-414d-a1b6-b0bd24c6b771" ],
|
|
"results" : {
|
|
"proteinExpression" : [ {
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|
"id" : "ca7b6082-f4ac-4be2-a28f-d1d73ad3eff3",
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|
"patient" : {
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|
"id" : "63f8fd7b-8127-4f3c-8843-aa9199e21c29",
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|
"type" : "Patient"
|
|
},
|
|
"protein" : {
|
|
"code" : "HGNC:391",
|
|
"display" : "AKT1",
|
|
"system" : "https://www.genenames.org/"
|
|
},
|
|
"value" : {
|
|
"code" : "2+",
|
|
"display" : "2+",
|
|
"system" : "dnpm-dip/mtb/ihc/protein-expression/result"
|
|
},
|
|
"tpsScore" : 64,
|
|
"icScore" : {
|
|
"code" : "3",
|
|
"display" : ">= 10%",
|
|
"system" : "dnpm-dip/mtb/ihc/protein-expression/ic-score"
|
|
},
|
|
"tcScore" : {
|
|
"code" : "6",
|
|
"display" : ">= 75%",
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|
"system" : "dnpm-dip/mtb/ihc/protein-expression/tc-score"
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}
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}, {
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"id" : "824afa8e-332f-498f-9e98-5e03ba072857",
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"patient" : {
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"id" : "63f8fd7b-8127-4f3c-8843-aa9199e21c29",
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|
"type" : "Patient"
|
|
},
|
|
"protein" : {
|
|
"code" : "HGNC:5173",
|
|
"display" : "HRAS",
|
|
"system" : "https://www.genenames.org/"
|
|
},
|
|
"value" : {
|
|
"code" : "unknown",
|
|
"display" : "untersucht, kein Ergebnis",
|
|
"system" : "dnpm-dip/mtb/ihc/protein-expression/result"
|
|
},
|
|
"tpsScore" : 67,
|
|
"icScore" : {
|
|
"code" : "2",
|
|
"display" : ">= 5%",
|
|
"system" : "dnpm-dip/mtb/ihc/protein-expression/ic-score"
|
|
},
|
|
"tcScore" : {
|
|
"code" : "4",
|
|
"display" : ">= 25%",
|
|
"system" : "dnpm-dip/mtb/ihc/protein-expression/tc-score"
|
|
}
|
|
}, {
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|
"id" : "697544ba-c91b-498c-825d-4768db65f064",
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"patient" : {
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|
"id" : "63f8fd7b-8127-4f3c-8843-aa9199e21c29",
|
|
"type" : "Patient"
|
|
},
|
|
"protein" : {
|
|
"code" : "HGNC:21597",
|
|
"display" : "ACAD10",
|
|
"system" : "https://www.genenames.org/"
|
|
},
|
|
"value" : {
|
|
"code" : "3+",
|
|
"display" : "3+",
|
|
"system" : "dnpm-dip/mtb/ihc/protein-expression/result"
|
|
},
|
|
"tpsScore" : 99,
|
|
"icScore" : {
|
|
"code" : "3",
|
|
"display" : ">= 10%",
|
|
"system" : "dnpm-dip/mtb/ihc/protein-expression/ic-score"
|
|
},
|
|
"tcScore" : {
|
|
"code" : "1",
|
|
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|
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|
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|
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},
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|
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|
} ]
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}
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