mirror of
https://github.com/dnpm-dip/mv64e-mtb-dto-go.git
synced 2025-07-01 18:32:55 +00:00
2629 lines
79 KiB
JSON
2629 lines
79 KiB
JSON
{
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|
"patient": {
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"id": "aca5a971-28be-4089-8128-0036a4fe6f1a",
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"gender": {
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"code": "male",
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"display": "Männlich",
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|
"system": "Gender"
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|
},
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|
"birthDate": "1961-09-01",
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|
"healthInsurance": {
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|
"type": {
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|
"code": "GKV",
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|
"display": "gesetzliche Krankenversicherung",
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|
"system": "http://fhir.de/CodeSystem/versicherungsart-de-basis"
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|
},
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|
"reference": {
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|
"id": "1234567890",
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|
"system": "https://www.dguv.de/arge-ik",
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"display": "AOK",
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|
"type": "HealthInsurance"
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}
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},
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"address": {
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"municipalityCode": "12345"
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},
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"age": {
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"value": 63,
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"unit": "Years"
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},
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"vitalStatus": {
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"code": "alive",
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"display": "Lebend",
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|
"system": "dnpm-dip/patient/vital-status"
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}
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|
},
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"episodesOfCare": [
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{
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"id": "5481850f-f266-4d2f-8fbc-6bb790680d8f",
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"patient": {
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"id": "aca5a971-28be-4089-8128-0036a4fe6f1a",
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"type": "Patient"
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},
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"period": {
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"start": "2024-12-24"
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},
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"diagnoses": [
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{
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"id": "c1731d5e-6cca-4f8e-bca6-de233926106e",
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"type": "MTBDiagnosis"
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}
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]
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}
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],
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"diagnoses": [
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{
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"id": "c1731d5e-6cca-4f8e-bca6-de233926106e",
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"patient": {
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"id": "aca5a971-28be-4089-8128-0036a4fe6f1a",
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"type": "Patient"
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},
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"recordedOn": "2023-03-01",
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"type": {
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"history": [
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{
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"value": {
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"code": "main",
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"display": "Hauptdiagnose",
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"system": "dnpm-dip/mtb/diagnosis/type"
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},
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"date": "2023-03-01"
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}
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]
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},
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"code": {
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"code": "C50.1",
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"display": "Bösartige Neubildung: Zentraler Drüsenkörper der Brustdrüse",
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"system": "http://fhir.de/CodeSystem/bfarm/icd-10-gm",
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"version": "2025"
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},
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"topography": {
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"code": "C50.1",
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"display": "Zentraler Drüsenkörper der Brust",
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"system": "urn:oid:2.16.840.1.113883.6.43.1",
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"version": "Zweite Revision"
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},
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"grading": {
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"history": [
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{
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|
"date": "2023-03-01",
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"codes": [
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{
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"code": "U",
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"display": "U = unbekannt",
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|
"system": "https://www.basisdatensatz.de/feld/161/grading"
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|
},
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|
{
|
|
"code": "2",
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|
"display": "Diffuse astrocytoma",
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|
"system": "dnpm-dip/mtb/who-grading-cns-tumors",
|
|
"version": "2021"
|
|
}
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|
]
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|
}
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|
]
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},
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"staging": {
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"history": [
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{
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|
"date": "2023-03-01",
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|
"method": {
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|
"code": "clinical",
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|
"display": "Klinisch",
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|
"system": "dnpm-dip/mtb/tumor-staging/method"
|
|
},
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|
"tnmClassification": {
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|
"tumor": {
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|
"code": "T1",
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|
"system": "UICC"
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|
},
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|
"nodes": {
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|
"code": "N2",
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|
"system": "UICC"
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|
},
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|
"metastasis": {
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|
"code": "Mx",
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|
"system": "UICC"
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|
}
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|
},
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|
"otherClassifications": [
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{
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|
"code": "unknown",
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|
"display": "Unbekannt",
|
|
"system": "dnpm-dip/mtb/diagnosis/kds-tumor-spread"
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|
}
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|
]
|
|
}
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|
]
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},
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"guidelineTreatmentStatus": {
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|
"code": "unknown",
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|
"display": "Unbekannt",
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|
"system": "dnpm-dip/mtb/diagnosis/guideline-treatment-status"
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|
},
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|
"notes": [
|
|
"Notes on the tumor diagnosis..."
|
|
]
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|
}
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],
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"familyMemberHistories": [
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{
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"id": "f982b161-f8a3-4b5b-a390-1ef0d84efc1b",
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"patient": {
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"id": "aca5a971-28be-4089-8128-0036a4fe6f1a",
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"type": "Patient"
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},
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|
"relationship": {
|
|
"code": "EXT",
|
|
"display": "Verwandter weiteren Grades",
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|
"system": "dnpm-dip/mtb/family-meber-history/relationship-type"
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|
}
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|
}
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|
],
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"guidelineTherapies": [
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{
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"id": "0c696b1a-d123-419b-9a6f-e79322392f4e",
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"patient": {
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"id": "aca5a971-28be-4089-8128-0036a4fe6f1a",
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"type": "Patient"
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},
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"reason": {
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"id": "c1731d5e-6cca-4f8e-bca6-de233926106e",
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"display": "Bösartige Neubildung: Zentraler Drüsenkörper der Brustdrüse",
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"type": "MTBDiagnosis"
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|
},
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|
"therapyLine": 3,
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"intent": {
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|
"code": "X",
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|
"display": "Keine Angabe",
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|
"system": "dnpm-dip/therapy/intent"
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|
},
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|
"category": {
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|
"code": "I",
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|
"display": "Intraopterativ",
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|
"system": "dnpm-dip/therapy/category"
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|
},
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|
"recordedOn": "2025-06-24",
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|
"status": {
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|
"code": "stopped",
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|
"display": "Abgebrochen",
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|
"system": "dnpm-dip/therapy/status"
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|
},
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|
"statusReason": {
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|
"code": "progression",
|
|
"display": "Progression",
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|
"system": "dnpm-dip/therapy/status-reason"
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|
},
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|
"period": {
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|
"start": "2024-04-24",
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|
"end": "2024-12-18"
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|
},
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|
"medication": [
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|
{
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|
"code": "L01EX02",
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|
"display": "Sorafenib",
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|
"system": "http://fhir.de/CodeSystem/bfarm/atc",
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|
"version": "2025"
|
|
}
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|
],
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|
"notes": [
|
|
"Notes on the therapy..."
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|
]
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|
},
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{
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"id": "da26f4c4-834e-4f6a-86eb-4df13c4a442f",
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"patient": {
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"id": "aca5a971-28be-4089-8128-0036a4fe6f1a",
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"type": "Patient"
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},
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"reason": {
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"id": "c1731d5e-6cca-4f8e-bca6-de233926106e",
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"display": "Bösartige Neubildung: Zentraler Drüsenkörper der Brustdrüse",
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|
"type": "MTBDiagnosis"
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|
},
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|
"therapyLine": 4,
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|
"intent": {
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|
"code": "X",
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|
"display": "Keine Angabe",
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|
"system": "dnpm-dip/therapy/intent"
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|
},
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|
"category": {
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|
"code": "A",
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|
"display": "Adjuvant",
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|
"system": "dnpm-dip/therapy/category"
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|
},
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|
"recordedOn": "2025-06-24",
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|
"status": {
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"code": "stopped",
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|
"display": "Abgebrochen",
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|
"system": "dnpm-dip/therapy/status"
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|
},
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|
"statusReason": {
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|
"code": "progression",
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|
"display": "Progression",
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|
"system": "dnpm-dip/therapy/status-reason"
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|
},
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|
"period": {
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|
"start": "2024-06-24",
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"end": "2025-02-24"
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|
},
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|
"medication": [
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|
{
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|
"code": "L01EX13",
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|
"display": "Gilteritinib",
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|
"system": "http://fhir.de/CodeSystem/bfarm/atc",
|
|
"version": "2025"
|
|
}
|
|
],
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|
"notes": [
|
|
"Notes on the therapy..."
|
|
]
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|
}
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|
],
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"guidelineProcedures": [
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{
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"id": "09ac6bfb-05bb-4c8f-b65a-dae96407939c",
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"patient": {
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"id": "aca5a971-28be-4089-8128-0036a4fe6f1a",
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"type": "Patient"
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|
},
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"reason": {
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|
"id": "c1731d5e-6cca-4f8e-bca6-de233926106e",
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|
"display": "Bösartige Neubildung: Zentraler Drüsenkörper der Brustdrüse",
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|
"type": "MTBDiagnosis"
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|
},
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|
"therapyLine": 3,
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|
"intent": {
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|
"code": "X",
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|
"display": "Keine Angabe",
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|
"system": "dnpm-dip/therapy/intent"
|
|
},
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|
"code": {
|
|
"code": "nuclear-medicine",
|
|
"display": "Nuklearmedizinische Therapie",
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|
"system": "dnpm-dip/mtb/procedure/type"
|
|
},
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|
"status": {
|
|
"code": "stopped",
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|
"display": "Abgebrochen",
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|
"system": "dnpm-dip/therapy/status"
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|
},
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|
"statusReason": {
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|
"code": "patient-death",
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|
"display": "Tod",
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|
"system": "dnpm-dip/therapy/status-reason"
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|
},
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|
"recordedOn": "2025-06-24",
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|
"period": {
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|
"start": "2024-12-24"
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|
},
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|
"notes": [
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|
"Notes on the therapeutic procedure..."
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|
]
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|
},
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|
{
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"id": "1d12955f-216f-4731-8a37-e2eca4c2a735",
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"patient": {
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"id": "aca5a971-28be-4089-8128-0036a4fe6f1a",
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"type": "Patient"
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},
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|
"reason": {
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|
"id": "c1731d5e-6cca-4f8e-bca6-de233926106e",
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|
"display": "Bösartige Neubildung: Zentraler Drüsenkörper der Brustdrüse",
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|
"type": "MTBDiagnosis"
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|
},
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|
"therapyLine": 1,
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|
"intent": {
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|
"code": "S",
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|
"display": "Sonstiges",
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|
"system": "dnpm-dip/therapy/intent"
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|
},
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|
"code": {
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|
"code": "surgery",
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|
"display": "OP",
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|
"system": "dnpm-dip/mtb/procedure/type"
|
|
},
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|
"status": {
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|
"code": "completed",
|
|
"display": "Abgeschlossen",
|
|
"system": "dnpm-dip/therapy/status"
|
|
},
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|
"statusReason": {
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|
"code": "progression",
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|
"display": "Progression",
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|
"system": "dnpm-dip/therapy/status-reason"
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|
},
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|
"recordedOn": "2025-06-24",
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|
"period": {
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|
"start": "2024-12-24"
|
|
},
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|
"notes": [
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|
"Notes on the therapeutic procedure..."
|
|
]
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|
}
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|
],
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|
"performanceStatus": [
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{
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"id": "7cf3d19b-a537-47e4-b7f0-d324e8b1ad70",
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"patient": {
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|
"id": "aca5a971-28be-4089-8128-0036a4fe6f1a",
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"type": "Patient"
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|
},
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|
"effectiveDate": "2025-06-24",
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|
"value": {
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|
"code": "1",
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|
"display": "ECOG 1",
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|
"system": "ECOG-Performance-Status"
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|
}
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|
}
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|
],
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|
"specimens": [
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{
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"id": "c3f30fe7-d193-4cde-a3c2-ef8f2497df51",
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"patient": {
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"id": "aca5a971-28be-4089-8128-0036a4fe6f1a",
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"type": "Patient"
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},
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"diagnosis": {
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"id": "c1731d5e-6cca-4f8e-bca6-de233926106e",
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|
"type": "MTBDiagnosis"
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|
},
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|
"type": {
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|
"code": "unknown",
|
|
"display": "Unbekannt",
|
|
"system": "dnpm-dip/mtb/tumor-specimen/type"
|
|
},
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|
"collection": {
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|
"date": "2025-06-24",
|
|
"method": {
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|
"code": "unknown",
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|
"display": "Unbekannt",
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|
"system": "dnpm-dip/mtb/tumor-specimen/collection/method"
|
|
},
|
|
"localization": {
|
|
"code": "unknown",
|
|
"display": "Unbekannt",
|
|
"system": "dnpm-dip/mtb/tumor-specimen/collection/localization"
|
|
}
|
|
}
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|
}
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|
],
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|
"priorDiagnosticReports": [
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{
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"id": "0209a1fa-3948-4bc5-a2f5-988818057544",
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"patient": {
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"id": "aca5a971-28be-4089-8128-0036a4fe6f1a",
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|
"type": "Patient"
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|
},
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|
"performer": {
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|
"id": "xyz",
|
|
"display": "Molekular-Pathologie UKx",
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|
"type": "Institute"
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|
},
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|
"issuedOn": "2025-06-24",
|
|
"specimen": {
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|
"id": "c3f30fe7-d193-4cde-a3c2-ef8f2497df51",
|
|
"type": "TumorSpecimen"
|
|
},
|
|
"type": {
|
|
"code": "fusion-panel",
|
|
"display": "Fusionspanel",
|
|
"system": "dnpm-dip/mtb/molecular-diagnostics/type"
|
|
},
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|
"results": [
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|
"Result of diagnostics..."
|
|
]
|
|
}
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|
],
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|
"histologyReports": [
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|
{
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"id": "1c51bb6f-b551-43a4-9923-6db7fe36440c",
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"patient": {
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"id": "aca5a971-28be-4089-8128-0036a4fe6f1a",
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"type": "Patient"
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},
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|
"specimen": {
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|
"id": "c3f30fe7-d193-4cde-a3c2-ef8f2497df51",
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|
"type": "TumorSpecimen"
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|
},
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|
"issuedOn": "2025-06-24",
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|
"results": {
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|
"tumorMorphology": {
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"id": "a177e88e-af76-45c8-ba93-e2f2339888a0",
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"patient": {
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"id": "aca5a971-28be-4089-8128-0036a4fe6f1a",
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"type": "Patient"
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|
},
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|
"specimen": {
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|
"id": "c3f30fe7-d193-4cde-a3c2-ef8f2497df51",
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|
"type": "TumorSpecimen"
|
|
},
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|
"value": {
|
|
"code": "9719/3",
|
|
"display": "Nasales NK/T-Zell-Lymphom",
|
|
"system": "urn:oid:2.16.840.1.113883.6.43.1",
|
|
"version": "Zweite Revision"
|
|
},
|
|
"note": "Notes..."
|
|
},
|
|
"tumorCellContent": {
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|
"id": "32605a2f-4c5c-4f5a-9909-326955405fe0",
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|
"patient": {
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|
"id": "aca5a971-28be-4089-8128-0036a4fe6f1a",
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|
"type": "Patient"
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|
},
|
|
"specimen": {
|
|
"id": "c3f30fe7-d193-4cde-a3c2-ef8f2497df51",
|
|
"type": "TumorSpecimen"
|
|
},
|
|
"method": {
|
|
"code": "histologic",
|
|
"display": "Histologisch",
|
|
"system": "dnpm-dip/mtb/tumor-cell-content/method"
|
|
},
|
|
"value": 0.40875903241796807
|
|
}
|
|
}
|
|
}
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|
],
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|
"ihcReports": [
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|
{
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|
"id": "ced8a836-262e-4067-b272-94c8f9222446",
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|
"patient": {
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"id": "aca5a971-28be-4089-8128-0036a4fe6f1a",
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|
"type": "Patient"
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|
},
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|
"specimen": {
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|
"id": "c3f30fe7-d193-4cde-a3c2-ef8f2497df51",
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|
"type": "TumorSpecimen"
|
|
},
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|
"issuedOn": "2025-06-24",
|
|
"results": {
|
|
"proteinExpression": [
|
|
{
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|
"id": "07bdd4f4-6df7-4c22-9ef2-2abb86cf4666",
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|
"patient": {
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|
"id": "aca5a971-28be-4089-8128-0036a4fe6f1a",
|
|
"type": "Patient"
|
|
},
|
|
"protein": {
|
|
"code": "HGNC:3942",
|
|
"display": "MTOR",
|
|
"system": "https://www.genenames.org/"
|
|
},
|
|
"value": {
|
|
"code": "not-exp",
|
|
"display": "Nicht exprimiert",
|
|
"system": "dnpm-dip/mtb/ihc/protein-expression/result"
|
|
},
|
|
"tpsScore": 21,
|
|
"icScore": {
|
|
"code": "1",
|
|
"display": ">= 1%",
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"system": "dnpm-dip/therapy/category"
|
|
},
|
|
"basedOn": {
|
|
"id": "1db4d8d9-d6c0-48d1-b135-d040403654f9",
|
|
"type": "MTBMedicationRecommendation"
|
|
},
|
|
"recordedOn": "2025-06-24",
|
|
"status": {
|
|
"code": "stopped",
|
|
"display": "Abgebrochen",
|
|
"system": "dnpm-dip/therapy/status"
|
|
},
|
|
"statusReason": {
|
|
"code": "progression",
|
|
"display": "Progression",
|
|
"system": "dnpm-dip/therapy/status-reason"
|
|
},
|
|
"recommendationFulfillmentStatus": {
|
|
"code": "partial",
|
|
"display": "Partiell",
|
|
"system": "dnpm-dip/therapy/recommendation-fulfillment-status"
|
|
},
|
|
"dosage": {
|
|
"code": "under-50%",
|
|
"display": "< 50 %",
|
|
"system": "dnpm-dip/therapy/dosage-density"
|
|
},
|
|
"period": {
|
|
"start": "2025-03-18",
|
|
"end": "2025-06-24"
|
|
},
|
|
"medication": [
|
|
{
|
|
"code": "L01XX77",
|
|
"display": "Adagrasib",
|
|
"system": "http://fhir.de/CodeSystem/bfarm/atc",
|
|
"version": "2025"
|
|
}
|
|
],
|
|
"notes": [
|
|
"Notes on the therapy..."
|
|
]
|
|
}
|
|
]
|
|
}
|
|
],
|
|
"responses": [
|
|
{
|
|
"id": "70c6b774-ca26-4837-b424-5fc37e9a1548",
|
|
"patient": {
|
|
"id": "aca5a971-28be-4089-8128-0036a4fe6f1a",
|
|
"type": "Patient"
|
|
},
|
|
"therapy": {
|
|
"id": "0b2347b7-3b85-442d-aa46-e9c5c9ee7802",
|
|
"type": "MTBSystemicTherapy"
|
|
},
|
|
"effectiveDate": "2025-06-03",
|
|
"method": {
|
|
"code": "RANO",
|
|
"display": "Nach RANO-Kriterien",
|
|
"system": "dnpm-dip/mtb/response/method"
|
|
},
|
|
"value": {
|
|
"code": "SD",
|
|
"display": "Stable Disease",
|
|
"system": "RECIST"
|
|
}
|
|
}
|
|
]
|
|
}
|