mirror of
https://github.com/dnpm-dip/mv64e-mtb-dto-go.git
synced 2025-09-13 10:42:52 +00:00
2510 lines
75 KiB
JSON
2510 lines
75 KiB
JSON
{
|
|
"patient": {
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"id": "fae56ea7-24a7-4556-82fb-2b5dde71bb4d",
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"gender": {
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|
"code": "female",
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"display": "Weiblich",
|
|
"system": "Gender"
|
|
},
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|
"birthDate": "1962-10-21",
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|
"dateOfDeath": "2009-10-21",
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|
"healthInsurance": {
|
|
"type": {
|
|
"code": "GKV",
|
|
"display": "gesetzliche Krankenversicherung",
|
|
"system": "http://fhir.de/CodeSystem/versicherungsart-de-basis"
|
|
},
|
|
"reference": {
|
|
"id": "1234567890",
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|
"system": "https://www.dguv.de/arge-ik",
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|
"display": "AOK",
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|
"type": "HealthInsurance"
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|
}
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|
},
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|
"address": {
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"municipalityCode": "12345"
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},
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"age": {
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"value": 47,
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"unit": "Years"
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},
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"vitalStatus": {
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|
"code": "deceased",
|
|
"display": "Verstorben",
|
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"system": "dnpm-dip/patient/vital-status"
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|
}
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|
},
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|
"episodesOfCare": [
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{
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"id": "d8b68856-3ba2-4d43-9653-6924897f5eab",
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"patient": {
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"id": "fae56ea7-24a7-4556-82fb-2b5dde71bb4d",
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"type": "Patient"
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},
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"period": {
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"start": "2025-01-09"
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},
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"diagnoses": [
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{
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"id": "19de7fac-c8db-4936-b8fe-c47acda6599b",
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"type": "MTBDiagnosis"
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}
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]
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}
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],
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"diagnoses": [
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{
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"id": "19de7fac-c8db-4936-b8fe-c47acda6599b",
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"patient": {
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"id": "fae56ea7-24a7-4556-82fb-2b5dde71bb4d",
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"type": "Patient"
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},
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"recordedOn": "2007-10-21",
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"type": {
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"history": [
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{
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"value": {
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"code": "main",
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"display": "Hauptdiagnose",
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|
"system": "dnpm-dip/mtb/diagnosis/type"
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|
},
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|
"date": "2007-10-21"
|
|
}
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|
]
|
|
},
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|
"code": {
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|
"code": "C72.5",
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|
"display": "Bösartige Neubildung: Sonstige und nicht näher bezeichnete Hirnnerven",
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|
"system": "http://fhir.de/CodeSystem/bfarm/icd-10-gm",
|
|
"version": "2025"
|
|
},
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|
"topography": {
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|
"code": "C72.5",
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"display": "Hirnnerven o.n.A.",
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"system": "urn:oid:2.16.840.1.113883.6.43.1",
|
|
"version": "Zweite Revision"
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|
},
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"grading": {
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|
"history": [
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{
|
|
"date": "2007-10-21",
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|
"codes": [
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{
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|
"code": "3",
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|
"display": "3 = schlecht differenziert",
|
|
"system": "https://www.basisdatensatz.de/feld/161/grading"
|
|
},
|
|
{
|
|
"code": "3",
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|
"display": "Anaplastic astrocytoma",
|
|
"system": "dnpm-dip/mtb/who-grading-cns-tumors",
|
|
"version": "2021"
|
|
}
|
|
]
|
|
}
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|
]
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|
},
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|
"staging": {
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|
"history": [
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{
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|
"date": "2007-10-21",
|
|
"method": {
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|
"code": "clinical",
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|
"display": "Klinisch",
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|
"system": "dnpm-dip/mtb/tumor-staging/method"
|
|
},
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|
"tnmClassification": {
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|
"tumor": {
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|
"code": "T0",
|
|
"system": "UICC"
|
|
},
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|
"nodes": {
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|
"code": "Nx",
|
|
"system": "UICC"
|
|
},
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|
"metastasis": {
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|
"code": "M0",
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|
"system": "UICC"
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|
}
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|
},
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|
"otherClassifications": [
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|
{
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|
"code": "unknown",
|
|
"display": "Unbekannt",
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|
"system": "dnpm-dip/mtb/diagnosis/kds-tumor-spread"
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|
}
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|
]
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|
}
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|
]
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},
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|
"guidelineTreatmentStatus": {
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|
"code": "impossible",
|
|
"display": "Leitlinientherapie nicht möglich",
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|
"system": "dnpm-dip/mtb/diagnosis/guideline-treatment-status"
|
|
},
|
|
"notes": [
|
|
"Notes on the tumor diagnosis..."
|
|
]
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|
}
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],
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"familyMemberHistories": [
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{
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"id": "0eac775e-ea13-49d4-a390-a5e99744ac6b",
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"patient": {
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"id": "fae56ea7-24a7-4556-82fb-2b5dde71bb4d",
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|
"type": "Patient"
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|
},
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|
"relationship": {
|
|
"code": "FAMMEMB",
|
|
"display": "Verwandter ersten Grades",
|
|
"system": "dnpm-dip/mtb/family-meber-history/relationship-type"
|
|
}
|
|
}
|
|
],
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"guidelineTherapies": [
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|
{
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"id": "af77fcc8-bcdc-41fb-9989-c4ad2fd9ce3c",
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"patient": {
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"id": "fae56ea7-24a7-4556-82fb-2b5dde71bb4d",
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"type": "Patient"
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},
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"reason": {
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"id": "19de7fac-c8db-4936-b8fe-c47acda6599b",
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"display": "Bösartige Neubildung: Sonstige und nicht näher bezeichnete Hirnnerven",
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|
"type": "MTBDiagnosis"
|
|
},
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|
"therapyLine": 8,
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|
"intent": {
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|
"code": "X",
|
|
"display": "Keine Angabe",
|
|
"system": "dnpm-dip/therapy/intent"
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|
},
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"category": {
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|
"code": "A",
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|
"display": "Adjuvant",
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|
"system": "dnpm-dip/therapy/category"
|
|
},
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|
"recordedOn": "2025-07-09",
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|
"status": {
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|
"code": "stopped",
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|
"display": "Abgebrochen",
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|
"system": "dnpm-dip/therapy/status"
|
|
},
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|
"statusReason": {
|
|
"code": "progression",
|
|
"display": "Progression",
|
|
"system": "dnpm-dip/therapy/status-reason"
|
|
},
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|
"period": {
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|
"start": "2024-03-09",
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|
"end": "2024-08-10"
|
|
},
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|
"medication": [
|
|
{
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|
"code": "L01XX58",
|
|
"display": "Epacadostat",
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|
"system": "http://fhir.de/CodeSystem/bfarm/atc",
|
|
"version": "2025"
|
|
}
|
|
],
|
|
"notes": [
|
|
"Notes on the therapy..."
|
|
]
|
|
},
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|
{
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"id": "f922939a-926e-4319-90e7-488ed9027d6d",
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"patient": {
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"id": "fae56ea7-24a7-4556-82fb-2b5dde71bb4d",
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"type": "Patient"
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},
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|
"reason": {
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|
"id": "19de7fac-c8db-4936-b8fe-c47acda6599b",
|
|
"display": "Bösartige Neubildung: Sonstige und nicht näher bezeichnete Hirnnerven",
|
|
"type": "MTBDiagnosis"
|
|
},
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|
"therapyLine": 5,
|
|
"intent": {
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|
"code": "X",
|
|
"display": "Keine Angabe",
|
|
"system": "dnpm-dip/therapy/intent"
|
|
},
|
|
"category": {
|
|
"code": "I",
|
|
"display": "Intraopterativ",
|
|
"system": "dnpm-dip/therapy/category"
|
|
},
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|
"recordedOn": "2025-07-09",
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|
"status": {
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|
"code": "stopped",
|
|
"display": "Abgebrochen",
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|
"system": "dnpm-dip/therapy/status"
|
|
},
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|
"statusReason": {
|
|
"code": "progression",
|
|
"display": "Progression",
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|
"system": "dnpm-dip/therapy/status-reason"
|
|
},
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|
"period": {
|
|
"start": "2024-04-09",
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|
"end": "2024-09-10"
|
|
},
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|
"medication": [
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|
{
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|
"code": "L01EG01",
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|
"display": "Temsirolimus",
|
|
"system": "http://fhir.de/CodeSystem/bfarm/atc",
|
|
"version": "2025"
|
|
}
|
|
],
|
|
"notes": [
|
|
"Notes on the therapy..."
|
|
]
|
|
}
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|
],
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|
"guidelineProcedures": [
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{
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"id": "b6d5bd15-356d-468a-a816-5fd955fc51a2",
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"patient": {
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"id": "fae56ea7-24a7-4556-82fb-2b5dde71bb4d",
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"type": "Patient"
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},
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|
"reason": {
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|
"id": "19de7fac-c8db-4936-b8fe-c47acda6599b",
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|
"display": "Bösartige Neubildung: Sonstige und nicht näher bezeichnete Hirnnerven",
|
|
"type": "MTBDiagnosis"
|
|
},
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|
"therapyLine": 2,
|
|
"intent": {
|
|
"code": "X",
|
|
"display": "Keine Angabe",
|
|
"system": "dnpm-dip/therapy/intent"
|
|
},
|
|
"code": {
|
|
"code": "radio-therapy",
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|
"display": "Strahlen-Therapie",
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|
"system": "dnpm-dip/mtb/procedure/type"
|
|
},
|
|
"status": {
|
|
"code": "on-going",
|
|
"display": "Laufend",
|
|
"system": "dnpm-dip/therapy/status"
|
|
},
|
|
"statusReason": {
|
|
"code": "regular-completion-with-substance-change",
|
|
"display": "Reguläres Ende mit Substanzwechsel",
|
|
"system": "dnpm-dip/therapy/status-reason"
|
|
},
|
|
"recordedOn": "2025-07-09",
|
|
"period": {
|
|
"start": "2025-01-09"
|
|
},
|
|
"notes": [
|
|
"Notes on the therapeutic procedure..."
|
|
]
|
|
}
|
|
],
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|
"performanceStatus": [
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|
{
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|
"id": "279b4954-7901-4b0b-89f3-1f90b12bcc02",
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|
"patient": {
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|
"id": "fae56ea7-24a7-4556-82fb-2b5dde71bb4d",
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|
"type": "Patient"
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|
},
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|
"effectiveDate": "2025-07-09",
|
|
"value": {
|
|
"code": "3",
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|
"display": "ECOG 3",
|
|
"system": "ECOG-Performance-Status"
|
|
}
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|
}
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|
],
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|
"specimens": [
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|
{
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"id": "c479b60d-c3e4-44d4-b0e5-c5891dd460ed",
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"patient": {
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"id": "fae56ea7-24a7-4556-82fb-2b5dde71bb4d",
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"type": "Patient"
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|
},
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|
"diagnosis": {
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|
"id": "19de7fac-c8db-4936-b8fe-c47acda6599b",
|
|
"type": "MTBDiagnosis"
|
|
},
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|
"type": {
|
|
"code": "FFPE",
|
|
"display": "FFPE",
|
|
"system": "dnpm-dip/mtb/tumor-specimen/type"
|
|
},
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|
"collection": {
|
|
"date": "2025-07-09",
|
|
"method": {
|
|
"code": "biopsy",
|
|
"display": "Biopsie",
|
|
"system": "dnpm-dip/mtb/tumor-specimen/collection/method"
|
|
},
|
|
"localization": {
|
|
"code": "local-recurrence",
|
|
"display": "Lokalrezidiv",
|
|
"system": "dnpm-dip/mtb/tumor-specimen/collection/localization"
|
|
}
|
|
}
|
|
}
|
|
],
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|
"priorDiagnosticReports": [
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{
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"id": "a7f20f97-c9ea-424d-add6-605dc2461782",
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"patient": {
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"id": "fae56ea7-24a7-4556-82fb-2b5dde71bb4d",
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|
"type": "Patient"
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|
},
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|
"performer": {
|
|
"id": "xyz",
|
|
"display": "Molekular-Pathologie UKx",
|
|
"type": "Institute"
|
|
},
|
|
"issuedOn": "2025-07-09",
|
|
"specimen": {
|
|
"id": "c479b60d-c3e4-44d4-b0e5-c5891dd460ed",
|
|
"type": "TumorSpecimen"
|
|
},
|
|
"type": {
|
|
"code": "fusion-panel",
|
|
"display": "Fusionspanel",
|
|
"system": "dnpm-dip/mtb/molecular-diagnostics/type"
|
|
},
|
|
"results": [
|
|
"Result of diagnostics..."
|
|
]
|
|
}
|
|
],
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|
"histologyReports": [
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|
{
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|
"id": "d57816b6-18b5-485d-9d7f-fc31004c429e",
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"patient": {
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"id": "fae56ea7-24a7-4556-82fb-2b5dde71bb4d",
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"type": "Patient"
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|
},
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"specimen": {
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|
"id": "c479b60d-c3e4-44d4-b0e5-c5891dd460ed",
|
|
"type": "TumorSpecimen"
|
|
},
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|
"issuedOn": "2025-07-09",
|
|
"results": {
|
|
"tumorMorphology": {
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|
"id": "21f1d157-6f40-4127-9b2f-91f32fedceb0",
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|
"patient": {
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"id": "fae56ea7-24a7-4556-82fb-2b5dde71bb4d",
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|
"type": "Patient"
|
|
},
|
|
"specimen": {
|
|
"id": "c479b60d-c3e4-44d4-b0e5-c5891dd460ed",
|
|
"type": "TumorSpecimen"
|
|
},
|
|
"value": {
|
|
"code": "9542/3",
|
|
"display": "Epitheloider maligner peripherer Nervenscheidentumor",
|
|
"system": "urn:oid:2.16.840.1.113883.6.43.1",
|
|
"version": "Zweite Revision"
|
|
},
|
|
"note": "Notes..."
|
|
},
|
|
"tumorCellContent": {
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"id": "81a42ef1-f9fe-4dfe-a876-cf1a262ca4ce",
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"patient": {
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"id": "fae56ea7-24a7-4556-82fb-2b5dde71bb4d",
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|
"type": "Patient"
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|
},
|
|
"specimen": {
|
|
"id": "c479b60d-c3e4-44d4-b0e5-c5891dd460ed",
|
|
"type": "TumorSpecimen"
|
|
},
|
|
"method": {
|
|
"code": "histologic",
|
|
"display": "Histologisch",
|
|
"system": "dnpm-dip/mtb/tumor-cell-content/method"
|
|
},
|
|
"value": 0.12624946426974026
|
|
}
|
|
}
|
|
}
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|
],
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|
"ihcReports": [
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|
{
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|
"id": "2046a862-66e0-4402-bb93-b64ce179d014",
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|
"patient": {
|
|
"id": "fae56ea7-24a7-4556-82fb-2b5dde71bb4d",
|
|
"type": "Patient"
|
|
},
|
|
"specimen": {
|
|
"id": "c479b60d-c3e4-44d4-b0e5-c5891dd460ed",
|
|
"type": "TumorSpecimen"
|
|
},
|
|
"issuedOn": "2025-07-09",
|
|
"results": {
|
|
"proteinExpression": [
|
|
{
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|
"id": "15d628bb-6e6a-435f-98dd-8bbc2f0311d1",
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|
"patient": {
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|
"id": "fae56ea7-24a7-4556-82fb-2b5dde71bb4d",
|
|
"type": "Patient"
|
|
},
|
|
"protein": {
|
|
"code": "HGNC:5173",
|
|
"display": "HRAS",
|
|
"system": "https://www.genenames.org/"
|
|
},
|
|
"value": {
|
|
"code": "1+",
|
|
"display": "1+",
|
|
"system": "dnpm-dip/mtb/ihc/protein-expression/result"
|
|
},
|
|
"tpsScore": 42,
|
|
"icScore": {
|
|
"code": "1",
|
|
"display": ">= 1%",
|
|
"system": "dnpm-dip/mtb/ihc/protein-expression/ic-score"
|
|
},
|
|
"tcScore": {
|
|
"code": "4",
|
|
"display": ">= 25%",
|
|
"system": "dnpm-dip/mtb/ihc/protein-expression/tc-score"
|
|
}
|
|
},
|
|
{
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|
"id": "a7af8f99-b917-4498-8c95-f09818906de2",
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|
"patient": {
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|
"id": "fae56ea7-24a7-4556-82fb-2b5dde71bb4d",
|
|
"type": "Patient"
|
|
},
|
|
"protein": {
|
|
"code": "HGNC:391",
|
|
"display": "AKT1",
|
|
"system": "https://www.genenames.org/"
|
|
},
|
|
"value": {
|
|
"code": "1+",
|
|
"display": "1+",
|
|
"system": "dnpm-dip/mtb/ihc/protein-expression/result"
|
|
},
|
|
"tpsScore": 90,
|
|
"icScore": {
|
|
"code": "0",
|
|
"display": "< 1%",
|
|
"system": "dnpm-dip/mtb/ihc/protein-expression/ic-score"
|
|
},
|
|
"tcScore": {
|
|
"code": "4",
|
|
"display": ">= 25%",
|
|
"system": "dnpm-dip/mtb/ihc/protein-expression/tc-score"
|
|
}
|
|
},
|
|
{
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{
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|
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