mirror of
https://github.com/dnpm-dip/mv64e-mtb-dto-rs.git
synced 2025-09-13 02:32:52 +00:00
3225 lines
97 KiB
JSON
3225 lines
97 KiB
JSON
{
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"patient": {
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"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
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"gender": {
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"code": "female",
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"display": "Weiblich",
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"system": "Gender"
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},
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"birthDate": "1983-11-26",
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|
"dateOfDeath": "2010-11-26",
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"healthInsurance": {
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|
"type": {
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|
"code": "GKV",
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|
"display": "gesetzliche Krankenversicherung",
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|
"system": "http://fhir.de/CodeSystem/versicherungsart-de-basis"
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|
},
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|
"reference": {
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|
"id": "1234567890",
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|
"system": "https://www.dguv.de/arge-ik",
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"display": "AOK",
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"type": "HealthInsurance"
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|
}
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},
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"address": {
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"municipalityCode": "12345"
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},
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"age": {
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"value": 27,
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"unit": "Years"
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},
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"vitalStatus": {
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|
"code": "deceased",
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"display": "Verstorben",
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"system": "dnpm-dip/patient/vital-status"
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|
}
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},
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"episodesOfCare": [
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{
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"id": "7b512517-1904-4efa-9b13-4295e84c8ae1",
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"patient": {
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"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
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"type": "Patient"
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},
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"period": {
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"start": "2025-02-19"
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},
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"diagnoses": [
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{
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"id": "ca45ee75-b6fb-4194-acd7-4197c96ba819",
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"type": "MTBDiagnosis"
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}
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]
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}
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],
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"diagnoses": [
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{
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"id": "ca45ee75-b6fb-4194-acd7-4197c96ba819",
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"patient": {
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"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
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"type": "Patient"
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},
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"recordedOn": "2008-04-26",
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"type": {
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"history": [
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{
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"value": {
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"code": "main",
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"display": "Hauptdiagnose",
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"system": "dnpm-dip/mtb/diagnosis/type"
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},
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"date": "2008-04-26"
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|
}
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]
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},
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"code": {
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|
"code": "C24.9",
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"display": "Bösartige Neubildung: Gallenwege, nicht näher bezeichnet",
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"system": "http://fhir.de/CodeSystem/bfarm/icd-10-gm",
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"version": "2025"
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},
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"topography": {
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"code": "C24.9",
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"display": "Gallenwege o.n.A.",
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"system": "urn:oid:2.16.840.1.113883.6.43.1",
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|
"version": "Zweite Revision"
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},
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"grading": {
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"history": [
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{
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|
"date": "2008-04-26",
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|
"codes": [
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{
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|
"code": "T",
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|
"display": "T = trifft nicht zu",
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|
"system": "https://www.basisdatensatz.de/feld/161/grading"
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|
},
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|
{
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|
"code": "4",
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|
"display": "Glioblastoma",
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|
"system": "dnpm-dip/mtb/who-grading-cns-tumors",
|
|
"version": "2021"
|
|
}
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|
]
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|
}
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|
]
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},
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|
"staging": {
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"history": [
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{
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"date": "2008-04-26",
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|
"method": {
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|
"code": "clinical",
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|
"display": "Klinisch",
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|
"system": "dnpm-dip/mtb/tumor-staging/method"
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|
},
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|
"tnmClassification": {
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"tumor": {
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|
"code": "T2",
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|
"system": "UICC"
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|
},
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|
"nodes": {
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|
"code": "N0",
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|
"system": "UICC"
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|
},
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"metastasis": {
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"code": "M1",
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|
"system": "UICC"
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|
}
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|
},
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|
"otherClassifications": [
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{
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|
"code": "unknown",
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|
"display": "Unbekannt",
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|
"system": "dnpm-dip/mtb/diagnosis/kds-tumor-spread"
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|
}
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]
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|
}
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|
]
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},
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"guidelineTreatmentStatus": {
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|
"code": "impossible",
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|
"display": "Leitlinientherapie nicht möglich",
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|
"system": "dnpm-dip/mtb/diagnosis/guideline-treatment-status"
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|
},
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|
"notes": [
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|
"Notes on the tumor diagnosis..."
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|
]
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}
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],
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"familyMemberHistories": [
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{
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"id": "82b89124-4e3d-435c-b253-9c0c01771b55",
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"patient": {
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"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
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"type": "Patient"
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},
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"relationship": {
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|
"code": "FAMMEMB",
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|
"display": "Verwandter ersten Grades",
|
|
"system": "dnpm-dip/mtb/family-meber-history/relationship-type"
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|
}
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|
}
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|
],
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"guidelineTherapies": [
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{
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"id": "53147d60-256e-4ea5-a07e-ea0847963240",
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"patient": {
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"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
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"type": "Patient"
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},
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"reason": {
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"id": "ca45ee75-b6fb-4194-acd7-4197c96ba819",
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"display": "Bösartige Neubildung: Gallenwege, nicht näher bezeichnet",
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"type": "MTBDiagnosis"
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|
},
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"therapyLine": 5,
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"intent": {
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"code": "X",
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|
"display": "Keine Angabe",
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|
"system": "dnpm-dip/therapy/intent"
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|
},
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"category": {
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"code": "S",
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"display": "Sonstiges",
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|
"system": "dnpm-dip/therapy/category"
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},
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"recordedOn": "2025-08-19",
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"status": {
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"code": "stopped",
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"display": "Abgebrochen",
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|
"system": "dnpm-dip/therapy/status"
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|
},
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|
"statusReason": {
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"code": "progression",
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|
"display": "Progression",
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|
"system": "dnpm-dip/therapy/status-reason"
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|
},
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"period": {
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|
"start": "2023-11-19",
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"end": "2024-02-18"
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},
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"medication": [
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{
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"code": "L01FX34",
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"display": "Odronextamab",
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"system": "http://fhir.de/CodeSystem/bfarm/atc",
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|
"version": "2025"
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|
}
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|
],
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|
"notes": [
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"Notes on the therapy..."
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|
]
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},
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{
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"id": "e5c57cbc-57e2-4ac6-a28f-c778e7365293",
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"patient": {
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"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
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"type": "Patient"
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},
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"reason": {
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"id": "ca45ee75-b6fb-4194-acd7-4197c96ba819",
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"display": "Bösartige Neubildung: Gallenwege, nicht näher bezeichnet",
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|
"type": "MTBDiagnosis"
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|
},
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|
"therapyLine": 6,
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|
"intent": {
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|
"code": "K",
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|
"display": "Kurativ",
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|
"system": "dnpm-dip/therapy/intent"
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|
},
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|
"category": {
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|
"code": "S",
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|
"display": "Sonstiges",
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|
"system": "dnpm-dip/therapy/category"
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|
},
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|
"recordedOn": "2025-08-19",
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"status": {
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"code": "stopped",
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|
"display": "Abgebrochen",
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|
"system": "dnpm-dip/therapy/status"
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|
},
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|
"statusReason": {
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|
"code": "progression",
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|
"display": "Progression",
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|
"system": "dnpm-dip/therapy/status-reason"
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|
},
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|
"period": {
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|
"start": "2023-10-19",
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|
"end": "2024-05-09"
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},
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|
"medication": [
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|
{
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|
"code": "L01XX58",
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|
"display": "Epacadostat",
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|
"system": "http://fhir.de/CodeSystem/bfarm/atc",
|
|
"version": "2025"
|
|
}
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|
],
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|
"notes": [
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|
"Notes on the therapy..."
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|
]
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|
}
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],
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"guidelineProcedures": [
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{
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"id": "edd079e7-e774-4d73-ae6c-0aa020209de8",
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"patient": {
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"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
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"type": "Patient"
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},
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"reason": {
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"id": "ca45ee75-b6fb-4194-acd7-4197c96ba819",
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"display": "Bösartige Neubildung: Gallenwege, nicht näher bezeichnet",
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"type": "MTBDiagnosis"
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|
},
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|
"therapyLine": 7,
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"intent": {
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|
"code": "K",
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|
"display": "Kurativ",
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|
"system": "dnpm-dip/therapy/intent"
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|
},
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|
"code": {
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|
"code": "nuclear-medicine",
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|
"display": "Nuklearmedizinische Therapie",
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|
"system": "dnpm-dip/mtb/procedure/type"
|
|
},
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|
"status": {
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|
"code": "stopped",
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|
"display": "Abgebrochen",
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|
"system": "dnpm-dip/therapy/status"
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|
},
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|
"statusReason": {
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|
"code": "toxicity",
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|
"display": "Toxizität",
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|
"system": "dnpm-dip/therapy/status-reason"
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|
},
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|
"recordedOn": "2025-08-19",
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|
"period": {
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|
"start": "2025-02-19"
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|
},
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|
"notes": [
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"Notes on the therapeutic procedure..."
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|
]
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|
},
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|
{
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"id": "28f4c210-4ed0-4d04-b86d-56846a9d7d03",
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"patient": {
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"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
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"type": "Patient"
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},
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|
"reason": {
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|
"id": "ca45ee75-b6fb-4194-acd7-4197c96ba819",
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|
"display": "Bösartige Neubildung: Gallenwege, nicht näher bezeichnet",
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|
"type": "MTBDiagnosis"
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|
},
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|
"therapyLine": 5,
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|
"intent": {
|
|
"code": "P",
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|
"display": "Palliativ",
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|
"system": "dnpm-dip/therapy/intent"
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|
},
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|
"code": {
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|
"code": "surgery",
|
|
"display": "OP",
|
|
"system": "dnpm-dip/mtb/procedure/type"
|
|
},
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|
"status": {
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|
"code": "completed",
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|
"display": "Abgeschlossen",
|
|
"system": "dnpm-dip/therapy/status"
|
|
},
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|
"statusReason": {
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|
"code": "medical-reasons",
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|
"display": "Medizinische Gründe",
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|
"system": "dnpm-dip/therapy/status-reason"
|
|
},
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|
"recordedOn": "2025-08-19",
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|
"period": {
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|
"start": "2025-02-19"
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|
},
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|
"notes": [
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|
"Notes on the therapeutic procedure..."
|
|
]
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|
}
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|
],
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"performanceStatus": [
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{
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"id": "d16d5132-aaa5-4dfb-8a2a-51502699e427",
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"patient": {
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"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
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"type": "Patient"
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|
},
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|
"effectiveDate": "2025-08-19",
|
|
"value": {
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|
"code": "1",
|
|
"display": "ECOG 1",
|
|
"system": "ECOG-Performance-Status"
|
|
}
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|
}
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|
],
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|
"specimens": [
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{
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"id": "f9c2810b-19e7-4236-98bd-a8687be994e3",
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"patient": {
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"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
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"type": "Patient"
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},
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"diagnosis": {
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"id": "ca45ee75-b6fb-4194-acd7-4197c96ba819",
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|
"type": "MTBDiagnosis"
|
|
},
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|
"type": {
|
|
"code": "FFPE",
|
|
"display": "FFPE",
|
|
"system": "dnpm-dip/mtb/tumor-specimen/type"
|
|
},
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|
"collection": {
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|
"date": "2025-08-19",
|
|
"method": {
|
|
"code": "cytology",
|
|
"display": "Zytologie",
|
|
"system": "dnpm-dip/mtb/tumor-specimen/collection/method"
|
|
},
|
|
"localization": {
|
|
"code": "metastasis",
|
|
"display": "Metastase",
|
|
"system": "dnpm-dip/mtb/tumor-specimen/collection/localization"
|
|
}
|
|
}
|
|
}
|
|
],
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|
"priorDiagnosticReports": [
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{
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"id": "308f6210-bbbb-4803-9412-bc245391879d",
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"patient": {
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"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
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|
"type": "Patient"
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|
},
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|
"performer": {
|
|
"id": "xyz",
|
|
"display": "Molekular-Pathologie UKx",
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|
"type": "Institute"
|
|
},
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|
"issuedOn": "2025-08-19",
|
|
"specimen": {
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|
"id": "f9c2810b-19e7-4236-98bd-a8687be994e3",
|
|
"type": "TumorSpecimen"
|
|
},
|
|
"type": {
|
|
"code": "karyotyping",
|
|
"display": "Karyotyping",
|
|
"system": "dnpm-dip/mtb/molecular-diagnostics/type"
|
|
},
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|
"results": [
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|
"Result of diagnostics..."
|
|
]
|
|
}
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|
],
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"histologyReports": [
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|
{
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"id": "de735f37-2c88-451a-a84c-9e7aa330d555",
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"patient": {
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"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
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"type": "Patient"
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},
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|
"specimen": {
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|
"id": "f9c2810b-19e7-4236-98bd-a8687be994e3",
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|
"type": "TumorSpecimen"
|
|
},
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|
"issuedOn": "2025-08-19",
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|
"results": {
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|
"tumorMorphology": {
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"id": "ff69e7c7-106e-4494-aa8e-f09122d525d1",
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"patient": {
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"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
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"type": "Patient"
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|
},
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|
"specimen": {
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|
"id": "f9c2810b-19e7-4236-98bd-a8687be994e3",
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|
"type": "TumorSpecimen"
|
|
},
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|
"value": {
|
|
"code": "9702/1",
|
|
"display": "Indolente T-Zell-lymphoproliferative Krankheit des Gastrointestinaltraktes",
|
|
"system": "urn:oid:2.16.840.1.113883.6.43.1",
|
|
"version": "Zweite Revision"
|
|
},
|
|
"note": "Notes..."
|
|
},
|
|
"tumorCellContent": {
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|
"id": "fec1a4d1-0bba-4c7c-8e17-bc59c0de7f12",
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|
"patient": {
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|
"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
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|
"type": "Patient"
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|
},
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|
"specimen": {
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|
"id": "f9c2810b-19e7-4236-98bd-a8687be994e3",
|
|
"type": "TumorSpecimen"
|
|
},
|
|
"method": {
|
|
"code": "histologic",
|
|
"display": "Histologisch",
|
|
"system": "dnpm-dip/mtb/tumor-cell-content/method"
|
|
},
|
|
"value": 0.9055861214418794
|
|
}
|
|
}
|
|
}
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|
],
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|
"ihcReports": [
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|
{
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|
"id": "833f35c8-2b3d-44a0-8504-2f8e2070863d",
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"patient": {
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"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
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|
"type": "Patient"
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|
},
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|
"specimen": {
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|
"id": "f9c2810b-19e7-4236-98bd-a8687be994e3",
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|
"type": "TumorSpecimen"
|
|
},
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|
"issuedOn": "2025-08-19",
|
|
"results": {
|
|
"proteinExpression": [
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|
{
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|
"id": "6e51d5db-38dd-4498-ad6b-11f1d53ed92c",
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|
"patient": {
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|
"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
|
|
"type": "Patient"
|
|
},
|
|
"protein": {
|
|
"code": "HGNC:6973",
|
|
"display": "MDM2",
|
|
"system": "https://www.genenames.org/"
|
|
},
|
|
"value": {
|
|
"code": "unknown",
|
|
"display": "untersucht, kein Ergebnis",
|
|
"system": "dnpm-dip/mtb/ihc/protein-expression/result"
|
|
},
|
|
"tpsScore": 73,
|
|
"icScore": {
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|
"code": "0",
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"dosage": {
|
|
"code": "under-50%",
|
|
"display": "< 50 %",
|
|
"system": "dnpm-dip/therapy/dosage-density"
|
|
},
|
|
"period": {
|
|
"start": "2010-07-23",
|
|
"end": "2010-11-26"
|
|
},
|
|
"medication": [
|
|
{
|
|
"code": "L01FX29",
|
|
"display": "Talquetamab",
|
|
"system": "http://fhir.de/CodeSystem/bfarm/atc",
|
|
"version": "2025"
|
|
}
|
|
],
|
|
"notes": [
|
|
"Notes on the therapy..."
|
|
]
|
|
}
|
|
]
|
|
},
|
|
{
|
|
"history": [
|
|
{
|
|
"id": "b4b536cf-5593-46b8-beba-85de615cea92",
|
|
"patient": {
|
|
"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
|
|
"type": "Patient"
|
|
},
|
|
"reason": {
|
|
"id": "ca45ee75-b6fb-4194-acd7-4197c96ba819",
|
|
"display": "Bösartige Neubildung: Gallenwege, nicht näher bezeichnet",
|
|
"type": "MTBDiagnosis"
|
|
},
|
|
"intent": {
|
|
"code": "P",
|
|
"display": "Palliativ",
|
|
"system": "dnpm-dip/therapy/intent"
|
|
},
|
|
"category": {
|
|
"code": "S",
|
|
"display": "Sonstiges",
|
|
"system": "dnpm-dip/therapy/category"
|
|
},
|
|
"basedOn": {
|
|
"id": "d1ee37d9-0557-437b-8213-89e81af01ce6",
|
|
"type": "MTBMedicationRecommendation"
|
|
},
|
|
"recordedOn": "2025-08-19",
|
|
"status": {
|
|
"code": "stopped",
|
|
"display": "Abgebrochen",
|
|
"system": "dnpm-dip/therapy/status"
|
|
},
|
|
"statusReason": {
|
|
"code": "progression",
|
|
"display": "Progression",
|
|
"system": "dnpm-dip/therapy/status-reason"
|
|
},
|
|
"recommendationFulfillmentStatus": {
|
|
"code": "partial",
|
|
"display": "Partiell",
|
|
"system": "dnpm-dip/therapy/recommendation-fulfillment-status"
|
|
},
|
|
"dosage": {
|
|
"code": "over-50%",
|
|
"display": ">= 50 %",
|
|
"system": "dnpm-dip/therapy/dosage-density"
|
|
},
|
|
"period": {
|
|
"start": "2010-07-16",
|
|
"end": "2010-11-26"
|
|
},
|
|
"medication": [
|
|
{
|
|
"code": "L01FX34",
|
|
"display": "Odronextamab",
|
|
"system": "http://fhir.de/CodeSystem/bfarm/atc",
|
|
"version": "2025"
|
|
}
|
|
],
|
|
"notes": [
|
|
"Notes on the therapy..."
|
|
]
|
|
}
|
|
]
|
|
}
|
|
],
|
|
"responses": [
|
|
{
|
|
"id": "675f6982-ef47-4a80-9b79-302e67ab76c4",
|
|
"patient": {
|
|
"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
|
|
"type": "Patient"
|
|
},
|
|
"therapy": {
|
|
"id": "cca7b7c6-bf76-4e44-bc3d-a2501bab8052",
|
|
"type": "MTBSystemicTherapy"
|
|
},
|
|
"effectiveDate": "2010-10-01",
|
|
"method": {
|
|
"code": "RECIST",
|
|
"display": "Nach RECIST-Kriterien",
|
|
"system": "dnpm-dip/mtb/response/method"
|
|
},
|
|
"value": {
|
|
"code": "MR",
|
|
"display": "Mixed Response",
|
|
"system": "RECIST"
|
|
}
|
|
},
|
|
{
|
|
"id": "852c7f10-d62c-4c8c-b062-9e7a9e3baae4",
|
|
"patient": {
|
|
"id": "d0c95174-b9ab-4c6c-8fda-d8176df6f216",
|
|
"type": "Patient"
|
|
},
|
|
"therapy": {
|
|
"id": "b4b536cf-5593-46b8-beba-85de615cea92",
|
|
"type": "MTBSystemicTherapy"
|
|
},
|
|
"effectiveDate": "2010-10-22",
|
|
"method": {
|
|
"code": "RECIST",
|
|
"display": "Nach RECIST-Kriterien",
|
|
"system": "dnpm-dip/mtb/response/method"
|
|
},
|
|
"value": {
|
|
"code": "CR",
|
|
"display": "Complete Response",
|
|
"system": "RECIST"
|
|
}
|
|
}
|
|
]
|
|
}
|